NT-proBNP and Myocardial Fibrosis

NT-proBNP and the diagnosis of exercise-induced myocardial ischaemia

BACKGROUND Amino terminal pro-B-type natriuretic peptide (NT-proBNP) is a sensitive marker of ventricular dysfunction. Exercise causes an increase in the secretion of NTproBNP, and with myocardial ischaemia the increase is more pronounced. This increase has been found to improve the diagnostic sensitivity of the stress ECG in diagnosing myocardial ischaemia in subjects with normal ventricular f...

Human ProBNP and proBNP-derived Peptides (BNP and NT-proBNP)

Brain natriuretic peptide (BNP) is a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties (1, 2, 3). BNP belongs to a family of structurally similar peptide hormones that also includes atrial natriuretic peptide (ANP), C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a 17 amino acid ring structure with a disulfide bond between two cy...

NT-proBNP testing - a health economics brochure

Measuring NT-proBNP in small animal practice

The general veterinary practitioner has the difficult task of identifying, managing and advising on prognosis of heart disease, often with limited access to diagnostic equipment, or with limited experience in performing diagnostic procedures such as echocardiography. Financial resources are often limited. Furthermore pet owners may be reluctant to allow diagnostic investigation of animals they ...

Choosing cut-offs for NT-proBNP